Medical Diagnostics & Clinical Scoring

Cockcroft-Gault Creatinine Clearance Calculator

Estimate adult creatinine clearance (CrCl) from age, sex, weight, and serum creatinine using the Cockcroft-Gault formula.

Estimated CrCl (Cockcroft-Gault)
64.8
Formula Used[(140 - age) * weight] / (72 * serum creatinine)

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Quick answer: Cockcroft-Gault CrCl

The Cockcroft-Gault calculator estimates adult creatinine clearance (CrCl) in mL/min from age, sex, weight, and serum creatinine. It is often used as a quick renal function estimate when medication references specify Cockcroft-Gault CrCl.

This page is for education and calculation support only. Medication dosing and kidney-function interpretation should be checked against local clinical guidance and a qualified clinician.

How to use the Cockcroft-Gault calculator

  1. Choose sex.
  2. Enter age in years.
  3. Enter the weight you intend to use in kilograms.
  4. Enter serum creatinine in mg/dL.
  5. Review the estimated CrCl in mL/min.

Cockcroft-Gault formula

CrCl = [ (140 - Age) * Weight ] / [ 72 * Serum Cr ] * (0.85 if Female)

Where:
CrCl=
Estimated creatinine clearance in mL/min
Age=
Age in years
Weight=
Weight in kilograms
Serum Cr=
Serum creatinine in mg/dL

For females, the result is multiplied by 0.85. The equation uses weight as a proxy for creatinine generation, so the chosen weight can materially change the estimate.

Important weight note

Some clinical workflows use actual body weight, ideal body weight, or adjusted body weight depending on body habitus and the medication context. This calculator uses the weight you enter directly. If you are calculating CrCl for drug dosing, confirm which weight basis your protocol expects.

When Cockcroft-Gault may be less reliable

Creatinine-based estimates can be less reliable in people with rapidly changing kidney function, unusual muscle mass, severe malnutrition, amputation, pregnancy, or acute illness. In those situations, clinical teams may prefer measured clearance or another kidney function estimate.

Frequently Asked Questions

It estimates adult creatinine clearance in mL/min. Many medication dosing references still specify Cockcroft-Gault CrCl, especially for renally cleared drugs.

Females generally have less muscle mass than males of the same weight, meaning they produce less endogenous creatinine. The 0.85 multiplier corrects for this physiological difference.

No. Cockcroft-Gault estimates creatinine clearance in mL/min, while many lab-reported eGFR values are normalized to body surface area in mL/min/1.73 m².

Enter the weight basis required by your clinical protocol or medication reference. Some workflows use actual, ideal, or adjusted body weight depending on the patient and drug.