Medical Diagnostics & Clinical Scoring

ECOG Performance Status

Determine the ECOG scale grade to assess an oncology patient's functional status and determine their suitability for chemotherapy or clinical trials.

Fully active, able to carry on all pre-disease performance

Yes

Restricted in physically strenuous activity but ambulatory

Confined to bed or chair >50% of waking hours

Completely disabled (cannot carry on any self-care)

Patient is deceased

ECOG Grade

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Clinical Overview

The ECOG Performance Status is a foundational metric in modern oncology. It is simpler and more universally used in clinical trials than the Karnofsky scale. It grades a patient's level of functioning on a scale of 0 (fully active) to 5 (dead).

Pathophysiology & Evidence

The physiological burden of cancer—cachexia, anemia, systemic inflammation—directly impacts physical capabilities. The ECOG score effectively captures this total systemic burden. An ECOG score of 3 or 4 generally contraindicates cytotoxic chemotherapy, as the risks of life-threatening toxicity far outweigh potential therapeutic benefits.

Formula Breakdown

Grade = 0 to 5

Frequently Asked Questions

Developed by the Eastern Cooperative Oncology Group, it is a 6-point scale used to assess how a patient's disease affects their daily living abilities.

Almost all oncology clinical trials require an ECOG score of 0 or 1 for enrollment to ensure the patient is healthy enough to tolerate experimental toxicities.

ECOG Performance Status

Clinical Overview

Pathophysiology & Evidence

Formula Breakdown

Frequently Asked Questions

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