Medical Diagnostics & Clinical Scoring

KDIGO Criteria for Acute Kidney Injury

Use the KDIGO criteria to diagnose and stage the severity of Acute Kidney Injury (AKI) based on serum creatinine and urine output.

KDIGO Stage
Stage 1
ManagementOptimization of fluid status, avoidance of nephrotoxins.

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KDIGO Criteria Overview

The Kidney Disease: Improving Global Outcomes (KDIGO) criteria provide a standardized staging system for Acute Kidney Injury (AKI). AKI is defined by a rapid decline in kidney function, often characterized by rising serum creatinine or falling urine output.

AKI Definition

AKI is diagnosed if one of the following occurs:

  • Increase in serum creatinine (SCr) by ≥0.3 mg/dL within 48 hours.
  • Increase in SCr to ≥1.5 times baseline within the prior 7 days.
  • Urine volume <0.5 mL/kg/h for 6 hours.

Stage based on max(SCr criteria, Urine Output criteria)

Frequently Asked Questions

AKI is an abrupt loss of function (hours to days), while Chronic Kidney Disease (CKD) involves long-term, permanent damage (over 3 months).

Urine output changes often precede creatinine elevations, allowing for earlier detection of renal stress.