Medical Diagnostics & Clinical Scoring

MDRD GFR (Glomerular Filtration Rate) Calculator

Calculate the estimated Glomerular Filtration Rate (eGFR) using the MDRD study equation for chronic kidney disease staging.

Est. GFR
61.8
CKD StageStage 2 (Mild)

Calculated locally in your browser. Fast, secure, and private.

Clinical Overview

The MDRD (Modification of Diet in Renal Disease) Equation revolutionized nephrology by providing a more accurate estimation of Glomerular Filtration Rate (GFR) than Cockcroft-Gault, particularly in patients with established chronic kidney disease (CKD).

Formula Breakdown

GFR=175∗(Cr−1.154)∗(Age−0.203)∗(0.742ifFemale)∗(1.212ifAfricanAmerican)\small \begin{aligned} GFR = 175 * (Cr^-1.154) * (Age^-0.203) * (0.742 if Female) * (1.212 if African American) \end{aligned}

It is used universally to stage CKD from Stage 1 (normal) to Stage 5 (kidney failure requiring dialysis). Note that many institutions are transitioning away from the race coefficient in favor of the newer 2021 CKD-EPI equation.

Frequently Asked Questions

The Modification of Diet in Renal Disease (MDRD) equation is used to estimate Glomerular Filtration Rate (GFR) to stage chronic kidney disease.

MDRD estimates GFR normalized to a standard body surface area (1.73 m²), making it excellent for diagnosing CKD but less accurate than Cockcroft-Gault for absolute renal clearance in unusually sized patients.

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