Medical Diagnostics & Clinical Scoring

RIFLE Criteria for AKI

Apply the RIFLE criteria to classify the severity of Acute Kidney Injury (AKI) based on serum creatinine changes and urine output decline.

RIFLE Category
Risk

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RIFLE Criteria Overview

The RIFLE criteria (Risk, Injury, Failure, Loss, and End-stage renal disease) was one of the first consensus definitions for Acute Kidney Injury (AKI). It classifies AKI based on severity (Risk, Injury, Failure) and outcome (Loss, End-stage).

Severity Stages

  • Risk: SCr increased ×1.5 or GFR decreased >25%.
  • Injury: SCr increased ×2.0 or GFR decreased >50%.
  • Failure: SCr increased ×3.0 or GFR decreased >75%.

Classification based on Serum Creatinine, GFR, and Urine Output

Frequently Asked Questions

While newer criteria like KDIGO are more common today, RIFLE remains an important foundational tool and is still found in historical clinical research.

Persistent Acute Kidney Failure defined as the complete loss of kidney function for more than 4 weeks.

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